Sunday, 31 May 2020

An AID[s] memoire to Covid 19 testing and tracing


I have been to a number of countries in Africa, but I have never been to the Democratic Republic of Congo. Its capital, Kinshasa, is famous for two reasons. The first is that it’s one of the world’s second-closest capital cities to another capital city (it faces Brazzaville, the capital of the Republic of Congo) with just the river Congo between them. The second reason is that a man living there was the first known case of someone infected with HIV-1. He tested positive in 1959. Over the intervening years, the HIV virus spread throughout the rest of the world. Since global surveillance and tracking of the epidemic began in 1983, 75 million people have been infected with the HIV virus and approximately 32 million people have died. Today it’s estimated that 19.5 million people are surviving and living with HIV thanks to antiretroviral treatment. However, it is estimated that there is almost the same number of people living with HIV, who don’t have access to any treatment at all. There is no cure for HIV.

In the early 1980s, public health doctors began to use the term ‘acquired immunodeficient syndrome’ or what we more commonly call to day AIDS. It has taken a long time for scientists and medical experts to understand the disease, and how it might be treated. I first became aware of AIDs in 1984, when a patient in the mental health service I was managing was admitted with an HIV positive diagnosis. He had acquired the virus through the contaminated blood product Factor VIII. Like many people at the time, we didn’t know a lot about the disease. There was a great deal of misinformation about whether you could catch AIDs from him by using a mug he had used, being in the same room as he was and so on. It was a difficult time, and he had certainly been subjected to much stigma induced anger and ignorance on the part of others.   

I don’t know what happened to him, as I left the service before he did. The treatments available then were crude in comparison to what is available today. These days there is a much greater understanding of how the virus might be transmitted to others, and rates of infection have dropped over the past five years in many parts of the world.  Sadly, sub-Saharan Africa, remains the most badly affected, and cases there account for over two thirds of all those living with HIV worldwide. The UK has made much progress in ending the HIV epidemic. In 2018, Public Health England published a report that detailed this progress and what still needs to be done. Testing for the virus remains a critical element in maintaining this progress.

Likewise, as the world learns to live with Covid19, a different type of virus but just as dangerous, testing will increasingly become an important part of dealing with the disease and containing the rate of infection. Whether we will ever get to a Covid19 version of the U=U stage is difficult to say as we simply don’t know enough about the disease yet. UK readers of this blog will be aware that a new track and trace testing initiative has been launched last week. The official description of what is involved can be found here, but if you, like me prefer pictures to words, have a look at this and perhaps this too.

Tracking and tracing those who test positive for Covid19 is of course, a ‘must do’ initiative in bringing the rate of infection under control. South Korea, Singapore, New Zealand, and parts of India have provided indisputable proof that this approach can have a massive impact on reducing the number of people who could unknowingly be the source of spreading the virus.

Will it work in the UK as well as it has done in these other countries? Two weeks ago, I would have answered with a resounding yes. Now with the Barnard Castle factor, I’m not so sure. And although I try hard not to do politics here, I just have to say that I, like so many others, am both angry and disappointed that Dominic Cummings chose to do what he did in the face of all those who made significant sacrifices in order to obey the rules. With hindsight, I perhaps should not have expected anything different from this man. He is part owner of the farm he went to in Durham. It’s a farm that has received over £235,000 in EU grants, despite Cummings being a decrier of the EU and being the major architect in developing Boris Johnson’s Brexit strategy. Hypocrisy doesn’t even begin to describe my feelings.

Anyway, now I have vented my spleen, back to the track and trace UK initiative. I sincerely hope that people do sign up for the app, and if contacted, do self-isolate and their families too. One of the major motivators that eventually led to the HIV epidemic being controlled was people seeing how easy the virus could be spread through engaging in everyday activities, including very loving and caring activities, and then seeing so many people succumb to AIDs and dying. Condom use, which at first was largely rejected, over time became the new normal. Nowadays, those people who can prove their adherence (that’s a good word – it’s a bit like authenticity) to antiretroviral treatment and who have an undetectable viral load, are affirmed as people unable to pass the HIV virus on. Hence the Undetectable = Untransmittable U=U notion. It’s an approach that’s based upon robust scientific evidence (we may have heard that before somewhere). If you cannot detect the virus in someone who previously tested positive for HIV, then they cannot transmit the virus to others.

We are still in the frontiers of understanding Covid19. We have a new antibody test, which will tell you if you have had Covid19 before. It won’t reassure you that you won’t get it again. There is not enough evidence yet to predict whether that might be the case. It also means we should not ignore social distancing measures. Even as the lockdown measures get scaled back, it still remains an imperative that if you don’t have to leave your home for work (or birthday celebrations), then stay at home, stay alert when out taking your daily exercise or shopping and if you get contacted by one of the 25,000 tracing folk, just be polite to them on the phone. They are back in employment and that has to be a good thing!


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